Possible food and drug interactions when taking Vicodin

Hydrocodone slows the nervous system. Alcohol can intensify this effect.

If hydrocodone is taken with certain other drugs, the effects of either may be increased, decreased, or altered. It is especially important to check with your doctor before combining Vicodin with the following:

Antianxiety drugs such as Valium and Librium
Antidepressant medications classified as "tricyclics," such as Elavil and Tofranil
Antihistamines such as Tavist
Drugs classified as MAO inhibitors, including the antidepressants Nardil and Parnate
Major tranquilizers such as Thorazine and Haldol
Other narcotic analgesics such as Demerol
Other central nervous system depressants such as Halcion and Restoril